MHC Class II (I-Ek), Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | MHC Class II (I-Ek), Mouse/Rat |
| Clone | REA510 |
| Host Species | Recombinant Human |
| Reactive Species | mouse, rat |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry, Immunofluorescence, MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MHC Class II (I-Ek) Antibody, anti-mouse/rat, Biotin, REAfinity™. Clone REA510 recognizes the mouse MHC class II alloantigen I-Ek. It also recognizes the rat MHC class II antigen RT1D and cells from mice of the H-2d, H-2p, and H-2r haplotypes. Cells from mice of the H-2b, H-2f, H-2g7, H-2q, and H-2s haplotypes do not express the I-E antigen. MHC class II is expressed on antigen-presenting cells, such as dendritic cells, monocytes, macrophages, B cells in lymphoid and non-lymphoid tissue, thymic epithelial cells, and on subsets of hematopoietic progenitor cells in the bone marrow. | Additional information: Clone REA510 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | RT1D |
| Gene, Accession # | Gene ID: 14969, 294270 |
| Catalog # | 130-107-816 |
| Price | $59 |
| Order / More Info | MHC Class II (I-Ek), Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Yelon, D. et al. (1999) Alterations in CD4-binding regions of the MHC class II molecule I-Ek do not impede CD4+ T cell development. J Immunol 162 (3): 1348-1358. | Vestberg, M. et al. (1998) Limited polymorphism in the first domain of the rat MHC class II RT1-D molecule. Immunogenetics 48 (5): 344-349. | Kasson, P. M. et al. (2000) Kinetics of peptide binding to the class II MHC protein I-Ek. Biochemistry 39 (5): 1048-1058. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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