CD28, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD28, Rat
CloneREA206
Host SpeciesRecombinant Human
Reactive Speciesrat
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionCD28 Antibody, anti-rat, PE, REAfinity™. Clone REA206 recognizes rat CD28, a 44 kDa glycoprotein also known as Tp44. CD28 is a homodimeric type I transmembrane protein of the Ig receptor superfamily, composed of disulfide-linked subunits. It is a costimulatory molecule which is expressed on most thymocytes, CD4+ and CD8+ T cells, and NK cells. Expression of CD28 is down-regulated at late stages of terminal effector T cell differentiation. Ligation of CD28 with CD80 (B7-1) and CD86 (B7-2) provides a costimulatory signal for T cell activation. | Additional information: Clone REA206 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesCD28RNA
Gene, Accession #Gene ID: 25660
Catalog #130-102-693
Price$66
Order / More InfoCD28, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesClark, G. J. et al. (1992) Identification of a cDNA encoding the rat CD28 homologue. Immunogenetics 35 (1): 54-57. | Guo, L. et al. (2003) Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation. Transpl Immunol. 12 (1): 41-48.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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