Integrin β6, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Integrin β6, Human |
| Clone | REA748 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Integrin β6 Antibody, anti-human, APC, REAfinity™. Clone REA748 recognizes the human integrin β6 antigen, a 95 kDa type I transmembrane glycoprotein which is a member of the integrin β family. Integrins are heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. Integrin β6, also known as ITGB6, is a receptor for fibronectin and cytotactin and interacts with coxsackievirus A9 and coxsackievirus B1 proteins. Integrin β6 forms heterodimers with integrin αV. Internalisation of integrin αV/β6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. | Additional information: Clone REA748 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | ITGB6, Integrin beta-6 |
| Gene, Accession # | Gene ID: 3694 |
| Catalog # | 130-111-454 |
| Price | $140 |
| Order / More Info | Integrin β6, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Agrez, M. V. et al. (1997) Integrin alpha v beta 6 enhances coxsackievirus B1 lytic infection of human colon cancer cells. Virology 239 (1): 71-77. | Ramsay, A. G. et al. (2007) HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6. Cancer Res. 67 (11): 5275-5284. | Gianni, T. et al. (2013) αvβ6- and αvβ8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion. PLoS Pathog. 9 (12): . |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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