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Antigenic Specificity | CD51, Human |
Clone | REA181 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | Vio Bright V423 conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD51 Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA181 recognizes CD51, also known as αV integrin, which is a 140 KDa single pass type I membrane protein. CD51 forms heterodimers with β1, β3, β5, or β6 inetgrins and serves as a receptor for diverse extra cellular matrix proteins such as fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, laminin, and matrix metalloproteinase-2. | Additional information: Clone REA181 displays negligible binding to Fc receptors. | |
Immunogen | n/a |
Other Names | ITGAV, MSK8, VNRA, VTNR |
Gene, Accession # | Gene ID: 3685 |
Catalog # | 130-131-574 |
Price | $201 |
Order / More Info | CD51, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Dahm, L. M. et al. (1998) Vitronectin regulates smooth muscle contractility via alphav and beta1 integrin. J. Cell. Sci. 111: 1175-1183. | Tuckwell, D. S. et al. (1993) Integrins: a review of their structure and mechanisms of ligand binding. Symp. Soc. Exp. Biol 47: 107-136. |