CD155, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD155, Mouse
CloneREA519
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatbiotin conjugate
Size9 µg in 300 µL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionCD155 Antibody, anti-mouse, Biotin, REAfinity™. Clone REA519 recognizes the mouse CD155 antigen, which is a 70 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. CD155, also known as poliovirus receptor (PVR), belongs to a large family of Ig molecules called nectins and nectin-like proteins, which mediate cell-cell adhesion, cell migration, and serve as entry receptors for viruses. CD155 and its family member CD112 (nectin-2) are the ligands for the activating cell-surface receptor DNAM-1 on CD8+ T cells and natural killer (NK) cells. Mouse CD155 is found on a wide variety of cells of hematopoietic origin, on CD4+ CD8+ thymocytes, regulatory T cells, other activated T cells, NKT cells, and at cell junctions on the primary vascular endothelial cells. | Additional information: Clone REA519 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesPVR, HVED, PVS, Taa1, TAGE4, mE4, NECL-5
Gene, Accession #Gene ID: 52118
Catalog #130-108-116
Price$30
Order / More InfoCD155, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesFuchs, A. et al. (2004) Cutting Edge: CD96 (Tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J Immunol 172: 3994-3998. | Tahara-Hanaoka, S. et al. (2006) Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor. Blood 107: 1491-1496. | Seth, S. et al. (2007) The murine pan T cell marker CD96 is an adhesion receptor for CD155 and nectin-1. Biochem. Biophys. Res. Commun. 364 (4): 959-965.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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