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Antigenic Specificity | CD10, Human |
Clone | REA877 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | VioBlue conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD10 Antibody, anti-human, VioBlue®, REAfinity™. Clone REA877 recognizes the human CD10 antigen, also known as the common acute lymphoblastic leukemia antigen (CALLA). CD10 is a 100 kDa cell surface molecule identical to human membrane-associated neutral endopeptidase (NEP) and also known as neprilysin or enkephalinase. | Human CD10 is expressed on a wide variety of normal and neoplastic cell types from different tissues including neural and hematopoietic cells. It is expressed on pre- and pro-B cells and is involved in B cell development and differentiation. The antigen is also present on mature neutrophils, T cell precursors, and some T cell leukemias/lymphomas. Furthermore, CD10 is expressed on neoplastic cells of several B lymphoid leukemias/lymphomas. | Additional information: Clone REA877 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | MME, CALLA, NEP, SFE, gp100, Neprilysin, Enkephalinase |
Gene, Accession # | Gene ID: 4311 |
Catalog # | 130-114-700 |
Price | $148 |
Order / More Info | CD10, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Shipp, M. A. and Look, A. T. (1993) Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key! Blood 82: 1052-1070. | Kalled, S. L. et al. (1995) The distribution of CD10 (NEP 24.11, CALLA) in human and mice is similar in non-lymphoid organs but differ within the hematopoietic system: absence on murine T and B lymphoid progenitors. Eur. J. Immunol. 25: 677-687. |