ELK-1 pS383, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityELK-1 pS383, Human
CloneREA896
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsIntracellular flow cytometry
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DescriptionELK-1 pS383 Antibody, anti-human, APC, REAfinity™. Clone REA896 recognizes the human transcription factor ELK-1, also known as ETS domain-containing protein ELK-1. ELK-1 is a member of the E twenty-six (Ets) oncogene family that consists of nuclear phosphoproteins, which are involved in many processes, e.g., differentiation, growth, and survival of cells, hematopoiesis, angiogenesis, wound healing, cancer, and inflammation. ELK-1 is a target of ERK1 and ERK2, which are both members of protein kinases, but also of JNK and p38 MAPK, which are all involved in diverse physiopathological forms of neuronal plasticity. ELK-1 is mainly found in brain, and it is strongly expressed in neurons. | Additional information: Clone REA896 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesELK1
Gene, Accession #Gene ID: 2002
Catalog #130-114-898
Price$142
Order / More InfoELK-1 pS383, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesGille, H. et al. (1995) ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO J. 14 (5): 951-962. | Sharrocks, A. D. (2001) The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2 (11): 827-837. | Besnard, A. et al. (2011) Elk-1 a transcription factor with multiple facets in the brain. Front. Neurosci. 5: 35.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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