iNKT, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityiNKT, Human
CloneREA1054
Host SpeciesRecombinant Human
Reactive Specieshuman, nonhuman primate
IsotypeIgG1
FormatAPC-Vio 770 conjugate
Size30 tests in 60 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptioniNKT Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA1054 recognizes human iNKT cells. Natural killer T (NKT) cells represent a distinct lymphocyte population that co-expresses T cell and NK cell surface markers. A subset of human NKT cells, referred to as iNKT cells, expresses an invariant TCR α-chain with certain TCR β-chains (Vα24-Jα18 combined with Vβ11). The iNKT cells are implicated in immunoregulatory processes such as tolerance, host defense, and tumor surveillance. | Additional information: Clone REA1054 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesTCR Vα24-JαQ, TCR Va24-JαQ
Gene, Accession #Gene ID: 28659, 28747, 28582, 28581, 933
Catalog #130-129-847
Price$166
Order / More InfoiNKT, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesMontoya, J. C. et al. (2007) Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 122: 1-14. | Exley, M. et al. (2008) Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop. Eur. J. Immunol. 38: 1756-1766.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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