CD85k (ILT3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD85k (ILT3), Human |
| Clone | REA141 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD85k (ILT3) Antibody, anti-human, PE-Vio® 770, REAfinity™. Clone REA141 recognizes CD85k, a member of regulatory immune receptor family, also known as leukocyte immunoglobulin-like receptor (LILRs/LIRs), immunoglobulin-like transcripts (ILTs), or CD85 family. CD85k is a type I membrane protein with two extracellular Ig-like domains, intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIM) and is expressed on monocytes, dendritic cells, and macrophages. In addition, suppressor T cells induce the expression of CD85k on antigen presenting cells. | Additional information: Clone REA141 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | LILRB4, ILT3, LIR-5 |
| Gene, Accession # | Gene ID: 11006 |
| Catalog # | 130-099-807 |
| Price | $162 |
| Order / More Info | CD85k (ILT3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Colonna, M. et al. (1997) A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J. Exp. Med. 186: 1809-1818. | Cheng, H. et al. (2011) Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): A myeloid inhibitory receptor involved in immune tolerance. J. Biol. Chem. 286: 18013-18025. | Sommer, A. and Fabri, M. (2015) Vitamin D regulates cytokine patterns secreted by dendritic cells to promote differentiation of IL-22-producing T cells. PLoS One 10 (6): e0130395. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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