CD48, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD48, Mouse
CloneREA1238
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionCD48 Antibody, anti-mouse, APC, REAfinity™. Clone REA1238 reacts with the CD48 mouse antigen, which is a 45 kDa GPI-linked glycoprotein also known as BCM1, blast-1 (human), or OX-45 (rat). CD48 belongs to the SLAM family including CD48, CD244, and CD150. These cell surface receptors were differentially expressed among functionally progenitors. Hematopoietic stem cells are highly purified as CD150-CD48-CD244- cells, multipotent hematopoietic progenitors are CD244+CD150-CD48- and most restricted progenitor cells are CD48+CD244+CD150-. In mouse, the ligands for CD48 are CD2 and CD244. | Additional information: Clone REA1238 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesBCM1, BLAST, Blast-1, Bcm-1, MEM-102, SLAMF2, Sgp-60
Gene, Accession #Gene ID: 12506
Catalog #130-124-727
Price$91
Order / More InfoCD48, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesLatchman, Y. et al. (1998) Cutting edge: Identification of the 2B4 molecule as a counter-receptor for CD48. J Immunol 161: 5809-5812. | Kato, K. et al. (1992) CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J. Exp. Med. 176: 1241. | Kiel, M. J. et al. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121 (7): 1109-1121.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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