CD142, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD142, Human
CloneHTF-1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1κ
FormatVioGreen conjugate
Size30 tests in 300 µL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionCD142 Antibody, anti-human, VioGreen™. The monoclonal antibody HTF-1 recognizes the 45 kDa type I transmembrane glycoprotein also known as TF (tissue factor). It functions as the high-affinity receptor for the coagulation factor VII and enables cells to initiate the blood coagulation cascades. It is reported, that the tissue factor exists in a membrane-bound and in a soluble form. It is expressed on activated endothelial cells and on monocytes, macrophages, and platelets, which are stimulated with inflammatory mediators such as LPS or TNF alpha. CD142 is also present on some tumor cells such as lung, breast, pancreatic, and colon, and on non-immune-tissues.
Immunogenn/a
Other NamesF3, Tissue Factor (TF), TF, TFA, CD142
Gene, Accession #Gene ID: 2152
Catalog #130-098-918
Price$174
Order / More InfoCD142, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesCarson, S. D. et al. (1994) Fibroblast tissue factor: calcium and ionophore induce shape changes, release of membrane vesicles, and redistribution of tissue factor antigen in addition to increased procoagulant activity. Blood 84: 526-534. | Bogdanov, V. Y. et al. (2003) Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein. Nat Med 9: 458-462. | Butenas, S. et al. (2008) Tissue factor activity and function in blood coagulation. Thromb. Res. 122: S42-S46. | Golino, P. et al. (2002) The inhibitors of the tissue factor: factor VII pathway. Thromb. Res. 106 (3): V257-V265.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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