CD41, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD41, Mouse |
| Clone | REA1194 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD41 Antibody, anti-mouse, APC-Vio® 770, REAfinity™. Clone REA1194 recognizes the mouse CD41 antigen, a single-pass type I membrane protein also known as integrin α2b or GPIIb. CD41 associates with CD61 to form the heterodimeric gpIIb/gpIIIa complex that is present on megakaryocytes, platelets, and early hematopoietic progenitors. The CD41/CD61 complex is a receptor for several adhesion molecules such as fibronectin, fibrinogen, plasminogen, and vitronectin and mediates platelets aggregation. CD41 expression marks the divergence of definitive hematopoietic precursors from the hemangioblasts or hemogenic endothelium during mouse embryonic development. | Additional information: Clone REA1194 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | ITGA2B, GPalpha IIb, GPIIb |
| Gene, Accession # | Gene ID: 16399 |
| Catalog # | 130-122-766 |
| Price | $160 |
| Order / More Info | CD41, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Mikkola, H. K. et al. (2003) Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood 101 (2): 508-516. | Thornton, M. A. et al. (1999) Characterization of the murine platelet alphaIIb gene and encoded cDNA. Blood 94 (11): 3947-3950. | Chen, Y. Q. et al. (1992) Identification of the alpha IIb beta 3 integrin in murine tumor cells. J. Biol. Chem. 267 (24): 17314-17320. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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