MSCA-1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | MSCA-1, Human |
| Clone | W8B2 |
| Host Species | Mouse |
| Reactive Species | human, nonhuman primate, other |
| Isotype | IgG1κ |
| Format | phycoerythrin (PE) conjugate |
| Size | 100 tests in 1 mL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MSCA-1 Antibody, anti-human, PE. Clone W8B2 recognizes the mesenchymal stromal cell antigen-1 (MSCA-1). MSCA-1 was shown to be restricted to mesenchymal stromal cells (MSCs) in the CD271bright population in bone marrow. These CD271brightCD45dim MSCs have a much higher clonogenic capacity compared to the CD271+CD45+ fraction in bone marrow. Therefore, MSCA-1 is a suitable marker to identify MSCs with a high proliferative potential. MSCA-1 expression was not found on placenta-derived MSCs after culture. |
| Immunogen | n/a |
| Other Names | ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP |
| Gene, Accession # | Gene ID: 249 |
| Catalog # | 130-093-587 |
| Price | $310 |
| Order / More Info | MSCA-1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Buhring, H. J. et al. (2007) Novel markers for the prospective isolation of human MSC. Ann. N. Y. Acad. Sci. 1106: 262-271. | Battula, V. L. et al. (2007) Human placenta and bone marrow derived MSC cultured in serum-free, b-FGF-containing medium express cell surface frizzled-9 and SSEA-4 and give rise to multilineage differentiation. Differentiation 75: 279-291. | Rozemuller, H. et al. (2010) Prospective isolation of mesenchymal stem cells from multiple mammalian species using cross-reacting anti-human monoclonal antibodies. Stem Cells Dev. 19: 1911-1921. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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