Cadherin-13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Cadherin-13, Human |
| Clone | REA752 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cadherin-13 Antibody, anti-human, APC, REAfinity™. Clone REA752 recognizes the human cadherin-13 antigen, also known as T-Cadherin or H-Cadherin (heart cadherin). Cadherin-13 is a transmembrane glycoprotein that mediates calcium-dependent intercellular adhesion. | It is suggested that cadherin-13 may function as a negative regulator of neural cell growth. Cadherin-13 is expressed human adult cerebral cortex, medulla, thalamus, and midbrain. In developing brain, a lower expression is found than in adult brain. Furthermore, cadherin-13 is expressed in the basal layer of the epidermis, lung, liver, kidney, and blood vessels. It is reported, that cadherin-13 could be used as a marker for breast cancer development. | Additional information: Clone REA752 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | p150, T-cad, T-cadherin |
| Gene, Accession # | Gene ID: 1012 |
| Catalog # | 130-111-450 |
| Price | $142 |
| Order / More Info | Cadherin-13, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Lee, S. W. (1996) H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer. Nat Med 2 (7): 776-782. | Takeuchi, T. et al. (2000) Expression of T-cadherin (CDH13, H-Cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cells. J. Neurochem. 74 (4): 1489-1497. | Philippova, M. et al. (2009) A guide and guard: the many faces of T-cadherin. Cell. Signal. 21 (7): 1035-1044. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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