HLA-B12, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityHLA-B12, Human
CloneREA138
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
FormatAPC-Vio 770 conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry
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DescriptionHLA-B12 Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA138 recognizes HLA B12, a class I human leukocyte antigen (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of three domains, of which one comprises the peptide binding groove. Antigens binding to class I molecules are 8-10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells. | Additional information: Clone REA138 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesHLA-B, AS, SPDA1
Gene, Accession #Gene ID: 3106
Catalog #130-099-858
Price$360
Order / More InfoHLA-B12, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesHewitt, E. W. et al. (2003) The MHC class I antigen presentation pathway: strategies for viral immune evasion. Immunology 110 (2): 163-169.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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