CD301 (CLEC10A), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD301 (CLEC10A), Human |
| Clone | REA586 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD301 (CLEC10A) Antibody, anti-human, PE, REAfinity™. Clone REA586 recognizes the human CD301 (CLEC10A) antigen, which is a 40 kDa type II transmembrane glycoprotein expressed by immature DCs and activated macrophages. CD301 is a member of the C-type lectin/C-type lectinl-ike domain (CTL/CTLD) superfamily which plays a role in cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, and immune response. CD301 binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These moieties are known as Tn-Ag which are expressed in a variety of carcinoma cells. | Additional information: Clone REA586 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Clec10a, C-type lectin superfamily member 14, Macrophage lectin 2, MGL |
| Gene, Accession # | Gene ID: 10462 |
| Catalog # | 130-127-916 |
| Price | $139 |
| Order / More Info | CD301 (CLEC10A), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Suzuki, N. et al. (1996) Molecular cloning and expression of cDNA encoding human macrophage C-type lectin. Its unique carbohydrate binding specificity for Tn antigen. J Immunol 156 (1): 128-135. | Napoletano, C. et al. (2012) Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation. Eur. J. Immunol. 42 (4): 936-945. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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