CD8b, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD8b, Mouse |
| Clone | REA793 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD8b Antibody, anti-mouse, PE, REAfinity™. Clone REA793 recognizes both alloantigeneic forms of the mouse CD8b antigen, a single-pass type I membrane protein also known as lymphocyte antigen 3 (Ly-3 or Lyt-3). The CD8 molecule is composed of two distinct polypeptide chains that pair on the cell surface either as a CD8aa homodimer or as a CD8ab heterodimer. These forms of the CD8 molecule are differentially expressed on functionally distinct CD8+ lymphocyte subsets. The CD8ab heterodimer is expressed on cytotoxic T cells and thymocytes. | Additional information: Clone REA793 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Cd8b1, Ly-3, Ly-C, Lyt-3 |
| Gene, Accession # | Gene ID: 12526 |
| Catalog # | 130-111-711 |
| Price | $72 |
| Order / More Info | CD8b, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Nakayama, K. et al. (1989) Isolation and characterization of the mouse CD8 beta-chain (Ly-3) genes. Absence of an intervening sequence between V- and J-like gene segments. J Immunol 142 (7): 2540-2546. | Blanc, D. et al. (1998) Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants. Eur. J. Immunol. 18 (4): 613-619. | Chang, H. C. et al. (2005) Structural and mutational analyses of a CD8alphabeta heterodimer and comparison with the CD8alphaalpha homodimer. Immunity 23 (6): 661-671. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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