TCRγ/δ, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TCRγ/δ, Rat |
| Clone | REA547 |
| Host Species | Recombinant Human |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | PE-Vio 770 conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCRγ/δ Antibody, anti-rat, PE-Vio® 770, REAfinity™. Clone REA547 recognizes the rat TCRγ/δ antigen. The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of an α- and a β-chain (TCRα/β) or a γ- and a δ-chain (TCRγ/δ). The γ and δ TCR-chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ-chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules. | Additional information: Clone REA547 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | gd TCR |
| Gene, Accession # | Gene ID: 24821, 290108 |
| Catalog # | 130-108-763 |
| Price | $53 |
| Order / More Info | TCRγ/δ, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Kuhnlein, P. et al. (1994) Identification and characterization of rat gamma/delta T lymphocytes in peripheral lymphoid organs, small intestine, and skin with a monoclonal antibody to a constant determinant of the gamma/delta T cell receptor. J Immunol 153 (3): 979-986. | Chien, Y. H. et al. (1996) Recognition by gamma/delta T cells. Annu. Rev. Immunol. 14: 511-532. | Smith-Garvin, J. E. et al. (2009) T cell activation. Annu. Rev. Immunol. 27: 591-619. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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