Edit |   |
---|---|
Antigenic Specificity | CD36, Mouse |
Clone | REA1184 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 150 µg in 1 mL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD36 Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA1184 recognizes the mouse CD36 antigen, which is a 88 kDa member of the class B scavenger receptor family. CD36 is not only expressed by platelets, but also by erythroid precursors, monocytes and macrophages, certain endothelial and specialized epithelial cells. On platelets, CD36 recognition of oxidized LDL contributes to their activation and provides a link between hyperlipidemia, oxidant stress, and the prothrombotic state. Cell-derived microparticles are also major ligands for CD36 and contribute to thrombus formation. Targeting CD36 is a promising avenue for the treatment of atheroinflammatory disorders. | Additional information: Clone REA1184 displays negligible binding to Fc receptors |
Immunogen | n/a |
Other Names | GPIV, gpIIIb, PAS IV, PAS-4, FAT |
Gene, Accession # | Gene ID: 12491 |
Catalog # | 130-122-086 |
Price | $400 |
Order / More Info | CD36, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Endemann, G. et al. (1993) CD36 is a receptor for oxidized low density lipoprotein. J. Biol. Chem. 268: 11811-11816. |