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Antigenic Specificity | Neurofilament H (200 kD), Human/Mouse |
Clone | REAL790 |
Host Species | Recombinant Human |
Reactive Species | human, mouse |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Neurofilament H (200 kD) Antibody, anti-human/mouse, FITC, REAdye_lease™. Clone REAL790 is an antibody fragment derived from the full Neurofilament H (200 kD) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL790 recognizes the Neurofilament H (200 kD) protein, which belongs to the type IV intermediate filament family. Neurofilaments are a major component of the neuronal cytoskeleton and a useful marker for distinguishing neurons which are positive for Neurofilament, from glia. It is found in several neural, neuroendocrine, and endocrine tumors, but also in carcinomas of skin and lung, paragangliomas and adrenal and extra-adrenal pheochromocytomas. Neurofilament H (200 kD) recognizes axons and some dendrites (except Purkinje cell dendrites) but not nerve cell bodies or tissues, except peripheral axons. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
Immunogen | n/a |
Other Names | Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, NEFH, NFH |
Gene, Accession # | n/a |
Catalog # | 130-129-274 |
Price | $400 |
Order / More Info | Neurofilament H (200 kD), Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Szaro, B. G. and Strong, M. J. (2010) Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease. Trends Neurosci. 33 (1): 27-37. | Wang, H. et al. (2012) Neurofilament proteins in axonal regeneration and neurodegenerative diseases. Neural Regen. Res. 7 (8): 620-626. | Basal, E. et al. (2018) Paraneoplastic neuronal intermediate filament autoimmunity. Neurology. 91 (18): e1677-e1689. |