Neurofilament H (200 kD), Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityNeurofilament H (200 kD), Human/Mouse
CloneREAL790
Host SpeciesRecombinant Human
Reactive Specieshuman, mouse
Isotypen/a
Formatfluorescein (FITC) conjugate
Size200 µL
Concentrationn/a
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence
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DescriptionNeurofilament H (200 kD) Antibody, anti-human/mouse, FITC, REAdye_lease™. Clone REAL790 is an antibody fragment derived from the full Neurofilament H (200 kD) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL790 recognizes the Neurofilament H (200 kD) protein, which belongs to the type IV intermediate filament family. Neurofilaments are a major component of the neuronal cytoskeleton and a useful marker for distinguishing neurons which are positive for Neurofilament, from glia. It is found in several neural, neuroendocrine, and endocrine tumors, but also in carcinomas of skin and lung, paragangliomas and adrenal and extra-adrenal pheochromocytomas. Neurofilament H (200 kD) recognizes axons and some dendrites (except Purkinje cell dendrites) but not nerve cell bodies or tissues, except peripheral axons. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogenn/a
Other NamesNeurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, NEFH, NFH
Gene, Accession #n/a
Catalog #130-129-274
Price$400
Order / More InfoNeurofilament H (200 kD), Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesSzaro, B. G. and Strong, M. J. (2010) Post-transcriptional control of neurofilaments: New roles in development, regeneration and neurodegenerative disease. Trends Neurosci. 33 (1): 27-37. | Wang, H. et al. (2012) Neurofilament proteins in axonal regeneration and neurodegenerative diseases. Neural Regen. Res. 7 (8): 620-626. | Basal, E. et al. (2018) Paraneoplastic neuronal intermediate filament autoimmunity. Neurology. 91 (18): e1677-e1689.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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