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Antigenic Specificity | CD337 (NKp30), Human |
Clone | AF29-4D12 |
Host Species | Mouse |
Reactive Species | human, nonhuman primate |
Isotype | IgG1κ |
Format | biotin conjugate |
Size | 100 tests in 1 mL |
Concentration | 1:11 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD337 (NKp30) Antibody, anti-human, Biotin. The CD337 receptor, also known as NKp30, is a 30 kDa type I membrane glycoprotein characterized by a single V-type Ig-like domain in the extracellular portion, and is found almost exclusively on the surface of resting or activated natural killer (NK) cells. CD337 is a member of the natural cytotoxicity receptor (NCR) family which trigger cytotoxicity in NK cells. CD337 is directly involved in target cell recognition and lysis and is expressed by all resting or activated NK cells and by a small subset of T cells. Its expression density parallels that of CD336 (NKp44). It seems to be involved in killing of cells which are lysed independently from CD336 (NKp44) and CD335 (NKp46). |
Immunogen | n/a |
Other Names | NCR3, 1C7, LY117, MALS, NKp30 |
Gene, Accession # | Gene ID: 259197 |
Catalog # | 130-092-553 |
Price | $264 |
Order / More Info | CD337 (NKp30), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Pende, D. et al. (1999) Identification and molecular characterization of Nkp30, a novel triggering receptor involved in natural cytotoxicity mediated by human natural killer cells. J. Exp. Med. 190: 1505-1516. | Moretta, L. and Moretta, A. (2004) Unravelling natural killer function: Triggering and inhibitory human NK receptors. EMBO J. 23: 255-259. | Sivori, S. et al. (2000) 2B4 functions as a co-receptor in human NK cell activation. Eur. J. Immunol. 30: 787-793. | Moretta, A. et al. (2001) Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19: 197-223. |