COX-4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCOX-4, Human
CloneREAL694
Host SpeciesRecombinant Human
Reactive Specieshuman
Isotypen/a
Formatphycoerythrin (PE) conjugate
Size200 µL
Concentrationn/a
ApplicationsMICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence
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DescriptionCOX-4 Antibody, anti-human, PE, REAdye_lease™. Clone REAL694 is an antibody fragment derived from the full COX-4 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL694 recognizes the human COX-4 protein, one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. COX-4 can be used to identify the inner membrane of mitochondria in immunfluorescence studies. Mutations in the gene have been associated with COX deficiency and Fanconi anemia. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
Immunogenn/a
Other NamesCOX IV-1 (Cytochrome c oxidase subunit IV isoform 1), Cytochrome c oxidase subunit 4 isoform 1, Cytochrome c oxidase polypeptide IV, COX4, COX IV
Gene, Accession #n/a
Catalog #130-126-578
Price$470
Order / More InfoCOX-4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesBottinger, L. et al. (2013) A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase. Mol. Biol. Cell 24 (17): 2609-2619. | Oliva, C. R. et al. (2015) Nuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomas. Oncotarget. 6 (6): 4330-4344.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

https://www.miltenyibiotec.com

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