CD137, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD137, Mouse |
| Clone | REA936 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD137 Antibody, anti-mouse, Biotin, REAfinity™. Clone REA936 recognizes the mouse CD137 antigen, a single-pass type I membrane protein also known as 4-1BB or TNFRSF9, which is a member of the TNFR superfamily. CD137 is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen-presenting cells delivers a bidirectional co-stimulatory signal. CD137 engagement is shown to be required for CD8+ T cell survival and memory formation. CD137 is reported to have a strong antagonistic effect in in vitro functional assays. | Additional information: Clone REA936 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TNFRSF9, 4-1BB, CDw137, ILA, Ly63, 41BB |
| Gene, Accession # | Gene ID: 21942 |
| Catalog # | 130-115-564 |
| Price | $64 |
| Order / More Info | CD137, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Pollok, K. E. et al. (1993) Inducible T cell antigen 4-1BB. Analysis of expression and function. J Immunol 150 (3): 771-781. | Tan, J. T. et al. (2000) Analysis of expression and function of the costimulatory molecule 4-1BB in alloimmune responses. Transplantation 70 (1): 175-183. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG