CD117, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD117, Human |
| Clone | REA996 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Vio Bright B515 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD117 Antibody, anti-human, Vio® Bright B515, REAfinity™. Clone REA996 recognizes the human CD117 antigen, also known as c-kit or SCF receptor. CD117 is a 145 kDa receptor tyrosine kinase involved in stem cell signaling, activation, and proliferation. It is expressed on about 1-3% of peripheral blood mononuclear cells (PBMCs) and cord blood cells and on up to 10% of bone marrow cells. CD117 is further expressed on basophils, myeloid dendritic cells, TCRα/β+ T cells, CD19+ B cells, and CD56+ NK cells, as well as on mast cells, melanocytes, and acute myeloid leukemia (AML) blasts. | Additional information: Clone REA996 displays negligible binding to Fc receptor. |
| Immunogen | n/a |
| Other Names | c-kit, KIT, PBT, SCFR |
| Gene, Accession # | Gene ID: 3815 |
| Catalog # | 130-116-733 |
| Price | $189 |
| Order / More Info | CD117, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Yarden, Y. et al. (1987) Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J. 6 (11): 3341-3351. | Buhring, H. J. et al. (1991) The product of the proto-oncogene c-kit (P145c-kit) is a human bone marrow surface antigen of hematopoietic precursor cells which is expressed on a subset of acute non-lymphoblastic cells. Leukemia 5: 854-860. | Guth, S. et al. (1995) Immunomagnetic isolation and surface phenotyping of human c-kit receptor-expressing cells from peripheral blood. 9th International Congress of Immunology: . |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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