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Antigenic Specificity | CD150 (SLAM), Mouse |
Clone | REA299 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD150 (SLAM) Antibody, anti-mouse, PE, REAfinity™. Clone REA299 recognizes the mouse CD150 antigen, a 75-95 kD single-pass type I membrane protein also known as signaling lymphocyte activation molecule (SLAM). CD150 belongs to the immunoglobulin superfamily and acts as a self ligand. Expression of CD150 is found on B cells, dendritic cells and activated/memory T cells. It is involved in functions such as stimulation, proliferation and inhibition of apoptosis of B cells, stimulation and IFN-γ production in Th1 T-cell clones and recently it has been identified as the second receptor for measles virus. In combination with CD48 and CD244, CD150 is a useful marker for hematopoietic stem cell studies. | Additional information: Clone REA299 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | SLAMF1, CDw150, ESTM51, IPO-3, SLAM |
Gene, Accession # | Gene ID: 27218 |
Catalog # | 130-125-987 |
Price | $71 |
Order / More Info | CD150 (SLAM), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Bleharski, J. R. et al. (2001) Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines. J Immunol 167 (6): 3167-3181. | Castro, A. G. et al. (1999) Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in T?1 and T?2 cells. J Immunol 163 (11): 5860-5870. | Wang, N. et al. (2004) The cell surface receptor SLAM controls T cell and macrophage functions. J Immunol 199 (9): 1255-1264. |