CD146 (LSEC), Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD146 (LSEC), Rat |
| Clone | REA697 |
| Host Species | Recombinant Human |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD146 (LSEC) Antibody, anti-rat, Biotin, REAfinity™. Clone REA697 recognizes the rat CD146 (LSEC) antigen, also known as Gicerin, MCAM, MUC18, or MEL-CAM. CD146 is a putative cell adhesion molecule of an immunoglobulin (Ig) superfamily which shows homophilic and heterophilic binding activities with two isoforms: S-gicerin, which has small cytoplasmic domain and the same extracellular domain as l-gicerin, shows stronger cell adhesion activity. CD146 is expressed on endothelial cells and a variety of tumor cells and is involved in cell adhesion and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. In rat, neurite promotion activity of CD146 from hippocampal neurons is reported. | Additional information: Clone REA697 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | MCAM, 1-gicerin, MUC18, S-endo, s-gicerin, Endo-CAM, Mel-CAM |
| Gene, Accession # | Gene ID: 78967 |
| Catalog # | 130-111-844 |
| Price | $202 |
| Order / More Info | CD146 (LSEC), Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Taira, E. et al. (2004) Characterization of Gicerin/MUC18/CD146 in the rat nervous system. J. Cell. Physiol. 198 (3): 377-387. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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