CD68, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD68, Rat
CloneREA237
Host SpeciesRecombinant Human
Reactive Speciesrat
IsotypeIgG1
FormatAPC-Vio 770 conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsIntracellular flow cytometry
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DescriptionCD68 Antibody, anti-rat, APC-Vio® 770, REAfinity™. Clone REA237 recognizes rat CD68, also known as macrosialin, which is a heavily glycosylated type I transmembrane protein of the LAMP (lysosomal-associated membrane protein) family. CD68 is expressed by the majority of tissue macrophages and weakly by peripheral blood granulocytes. It is also present on rat Kupffer cells but absent from rat liver endothelial cells. The expression of rat CD68 is predominantly intracellular, but it is reported that weak cell surface expression also occurs as well. CD68 functions as a macrophage receptor for oxidized low density lipoprotein. | Additional information: Clone REA237 displays negligible binding to Fc receptors. |
Immunogenn/a
Other Namesn/a
Gene, Accession #Gene ID: 287435
Catalog #130-125-103
Price$159
Order / More InfoCD68, Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesRabinowitz, S. S. et al. (1991) Macrosialin, a macrophage-restricted membrane sialoprotein differentially glycosylated in response to inflammatory stimuli. J. Exp. Med. 174 (4): 827-836. | Van Velzen, A. G. et al. (1997) Characterization of a receptor for oxidized low-density lipoproteins on rat Kupffer cells: similarity to macrosialin. Biochem. J. 1 (322): 411-415.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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