CD269 (BCMA), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD269 (BCMA), Mouse |
| Clone | REA550 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | phycoerythrin (PE) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD269 (BCMA) Antibody, anti-mouse, PE, REAfinity™. Clone REA550 recognizes the mouse CD269 antigen, which is also known as B cell maturation protein BCMA. CD269 is a member of the TNF receptor superfamily. Its binding to BLyS and APRIL activates transcription factor NF-κB and stimulates IgM production by peripheral blood B cells. A soluble form of BCMA, which inhibits the proliferative activity of APRIL in vitro, decreases tumor cell proliferation in nude mice. CD269 has been detected in immune organs such as spleen, thymus, bone marrow, and heart, as well as at lower levels in kidney and lung and is preferentially expressed in mature B lymphocytes. | Additional information: Clone REA550 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TNFRSF17, Bcm, BCMA, Tnfrsf13, Tnfrsf13a |
| Gene, Accession # | Gene ID: 21935 |
| Catalog # | 130-121-443 |
| Price | $71 |
| Order / More Info | CD269 (BCMA), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Rennert, P. et al. (2000) A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member april, inhibits tumor cell growth. J. Exp. Med. 192: 1677-1684. | Madry, C. et al. (1998) The characterization of murine BCMA gene defines it as a new member of the tumor necrosis factor receptor superfamily. Int. Immunol. 10 (11): 1693-1702. | Marsters, S. A. et al. (2000) Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI. Curr. Biol. 10 (13): 785-788. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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