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Antigenic Specificity | CD16, Human |
Clone | REA1324 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 200 µL |
Concentration | 1:50 |
Applications | Mass cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD16 Antibody, anti-human, PE, REAfinity™. Clone REA1324 recognizes the human CD16 antigen, a single-pass type I membrane protein which is also known as low affinity immunoglobulin gamma Fc region receptor III (FcRIII). CD16 is a 50-80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form (CD16A) is found on human NK cells, subsets of T cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form (CD16b) is present on granulocytes. The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone REA1324 recognizes both CD16A and CD16B. | Additional information: Clone REA1324 displays negligible binding to Fc receptors. | | | | |
Immunogen | n/a |
Other Names | FCGR3A, FCGR3B, FcR-10, IGFR3, IMD20, FcRIII |
Gene, Accession # | Gene ID: 2214, 2215 |
Catalog # | 130-128-774 |
Price | $285 |
Order / More Info | CD16, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | n/a |