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Antigenic Specificity | CD83, Mouse |
Clone | REA304 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD83 Antibody, anti-mouse, PE, REAfinity™. Clone REA304 recognizes the mouse CD83 antigen, a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily. Murine CD83 is moderately expressed on resting T cells and DC, but strongly increases in its expression on T cells following activation with antigenic peptides or T cell receptor-specific monoclonal antibody. When returning to the resting state, T cells down-regulate CD83 again. Histological analysis of serial spleen sections revealed a CD83 expression pattern resembling that of MIDC-8, a known murine DC marker molecule. | Additional information: Clone REA304 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | B-cell activation protein, Cell surface protein HB15 |
Gene, Accession # | Gene ID: 12522 |
Catalog # | 130-104-474 |
Price | $72 |
Order / More Info | CD83, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Luthje, K. et al. (2008) CD83 regulates splenic B cell maturation and peripheral B cell homeostasis. Int. Immunol. 20 (8): 949-960. | Twist, C. J. et al. (1998) The mouse CD83 gene: structure, domain organization, and chromosome localization. Immunogenetics 48 (6): 383-393. | Wolenski, M. et al. (2003) Expression of CD83 in the murine immune system. Med. Microbiol. Immun. 192 (4): 189-192. |