Phospholamban, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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|---|---|
| Antigenic Specificity | Phospholamban, Human |
| Clone | REAL773 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Phospholamban Antibody, anti-human, PE, REAdye_lease™. Clone REAL773 is an antibody fragment derived from the full Phospholamban antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL773 recognizes Phospholamban (PLB), also known as Cardiac phospholamban, a micropeptide protein that in humans is encoded by the PLN gene. Phospholamban (PLB) modulates the contractility of the heart muscle and it plays an important role in calcium homeostasis. Phospolamban (PLB) is a key regulator of cardiac diastolic function. Mutations in the PLN gene are caused in human dilated Cardiomyopathy. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | PLB, Cardiac phospholamban, PLN |
| Gene, Accession # | n/a |
| Catalog # | 130-129-695 |
| Price | $470 |
| Order / More Info | Phospholamban, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Schmitt, J. P. et al. (2003) Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science 299 (5611): 1410-1413. | Shaikh, S. A. et al. (2016) Phospholamban and sarcolipin: Are they functionally redundant or distinct regulators of the Sarco(Endo)Plasmic Reticulum Calcium ATPase? J. Mol. Cell. Cardiol. 91: 81-91. | Te Rijdt, W. P. et al. (2019) Distinct molecular signature of phospholamban p.Arg14del arrhythmogenic cardiomyopathy Cardiovasc Pathol. 40: 2-6. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG