Nur77, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Nur77, Mouse |
| Clone | REA704 |
| Host Species | Recombinant Human |
| Reactive Species | mouse, human |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Nur77 Antibody, anti-mouse, APC, REAfinity™. Clone REA704 recognizes the mouse Nur77 antigen, a member of the steroid/ thyroid hormone receptor superfamily of intracellular transcription factors. Nur77 is an inducible orphan nuclear receptor also known as NR4A1 or nerve growth factor IB (NGFI-B) and plays a role in cell cycle mediation, inflammation, and apoptosis and is involved in mediation of inflammatory responses in macrophages. Nur77 expression is found on thymocytes and T cell lines and is mainly expressed in testis but also in brain and muscle tissue. | Additional information: Clone REA704 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | NR4A1, TR3, NGFI-B, NAK1, N10, TISI |
| Gene, Accession # | Gene ID: 15370 |
| Catalog # | 130-111-418 |
| Price | $88 |
| Order / More Info | Nur77, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Cunningham, N. R. et al. (2006) Immature CD4+CD8+ thymocytes and mature T cells regulate Nur77 distinctly in response to TCR stimulation. J Immunol 177 (10): 6660-6666. | Pei, L. et al. (2006) Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77. Mol Endocrinol. 20 (4): 786-794. | Tao, R. et al. (2008) Resistance of Foxp3+ regulatory T cells to Nur77-induced apoptosis promotes allograft survival. PLoS One 3 (5): e2321. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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