CD16, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD16, Human |
| Clone | VEP13 |
| Host Species | Mouse |
| Reactive Species | human, nonhuman primate |
| Isotype | IgMκ |
| Format | biotin conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD16 Antibody, anti-human, Biotin. CD16 is a 50-80 kDa glycoprotein that is expressed in two different isoforms. The transmembrane form is found on human NK cells, macrophages, and mast cells, while the glycosylphosphatidylinositol (GPI)-linked form is present on neutrophils. | The human CD16 antigen is a low-affinity receptor for aggregated IgG. The transmembrane form plays a role in signal transduction, NK cell activation, and antibody-dependent cellular cytotoxicity. Clone VEP13 recognizes both the extracellular domain of the transmembrane form as well as the GPI-linked form of the human CD16 antigen. CD16 is expressed on the majority of rhesus monkey NK cells and on a subset of monocytes but not on granulocytes. |
| Immunogen | n/a |
| Other Names | FcγRIIIA, FcγRIIIB, FcR-10, IGFR3, IMD20 |
| Gene, Accession # | Gene ID: 2214 |
| Catalog # | 130-113-944 |
| Price | $93 |
| Order / More Info | CD16, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Schlaepfer, E. et al. (2008) Anti-HIV activity mediated by natural killer and CD8+ cells after toll-like receptor 7/8 triggering. PLoS One 3 (4): e1999. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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