CD57, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-CD57, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD57, Human |
| Clone | REA769 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PE-Vio 615 conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD57 Antibody, anti-human, PE-Vio® 615, REAfinity™. Clone REA769 recognizes the human CD57 antigen. CD57, also known as HNK-1 or Leu-7, is an antigenic oligosaccharide moiety detected on extracellular proteins of certain cell types. In blood, CD57 is found on 15-20% of mononuclear cells, including subsets of NK and T cells, though not on erythrocytes, monocytes, granulocytes, or platelets. Also, CD57 expression can be found on a variety of neural cell types. CD57 has been shown to be expressed on late stage effector CD8+ T cells. The frequency of CD57+ T lymphocytes is raised in a variety of diseases. CD57 expression is also increased on chronically activated CD8+ T cells in persistent viral infections, such as HIV. | Additional information: Clone REA769 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | B3GAT1, GLCATP, GLCUATP, HNK-1, Leu-7, NK-1 |
| Gene, Accession # | Gene ID: 27087 |
| Catalog # | 130-111-815 |
| Price | $350 |
| Order / More Info | CD57, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Mechtersheimer, G. et al. (1991) Expression of the natural killer cell-associated antigens CD56 and CD57 in human neural and striated muscle cells and in their tumors. Cancer Res. 51: 1300-1307. | Dupuy d'Angeac, A. et al. (1993) Increased percentage of CD3+, CD57+ lymphocytes in patients with rheumatoid arthritis. Correlation with duration of disease. Arthritis Rheum 36: 608-612. | Ong, E. et al. (2002) Biosynthesis of HNK-1 glycans on O-linked oligosaccharides attached to the neural cell adhesion molecule (NCAM): the requirement for core 2 β1,6-N-acetylglucosaminyltransferase and the muscle-specific domain in NCAM. J. Biol. Chem. 277: 18182-18190. | Brenchley, J. M. et al. (2003) Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood 101: 2711-2720. | Palmer, B. E. et al. (2005) Functional and phenotypic characterization of CD57+CD4+ T cells and their association with HIV-1-induced T cell dysfunction. J Immunol 175: 8415-8423. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG
Return to Antibodies