CD180 (RP105), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD180 (RP105), Human
CloneMHR73-11
Host SpeciesMouse
Reactive Specieshuman, nonhuman primate
IsotypeIgG1κ
Formatphycoerythrin (PE) conjugate
Size100 tests in 1 mL
Concentration1:11
ApplicationsFlow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
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DescriptionCD180 (RP105) Antibody, anti-human, PE. The monoclonal antibody MHR73-11 recognizes human CD180, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) family. The extracellular domain of CD180 is associated with MD-1, which forms the cell surface complex RP105/MD-1. Together with TLR4, it mediates B cell recognition and signaling of LPS. CD180 is expressed on mature B cells in mantle zones, on monocytes, macrophages, and dendritic cells.
Immunogenn/a
Other NamesLY64, Ly78, RP105
Gene, Accession #Gene ID: 4064
Catalog #130-098-488
Price$310
Order / More InfoCD180 (RP105), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesMiura, Y. et al. (1998) RP105 Is associated with MD-1 and transmits an activation signal in human B cells. Blood 92: 2815 - 2822. | Divanovic, S. et al. (2005) Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105. Nat Immunol 6 (6): 571-578. | Ogata, H. et al. (2000) The toll-like receptor protein Rp105 regulates lipopolysaccharide signaling in B cells. J. Exp. Med. 192: 23-30.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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