Nestin, Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityNestin, Mouse/Rat
CloneREA575
Host SpeciesRecombinant Human
Reactive Speciesmouse, rat
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size30 µg in 200 µL
Concentration1:50
ApplicationsIntracellular flow cytometry
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DescriptionNestin Antibody, anti-mouse/rat, PE, REAfinity™. Clone REA575 recognizes the mouse and rat nestin antigen, a type VI intermediate filament protein, mainly expressed in the developing central nervous system and skeletal muscles. In adult eye, nestin is present in the optic nerve but also transiently expressed in the midembryonic mouse heart. Nestin plays a role in regulation of the assembly and disassembly of phosphorylated vimentin intermediate filaments during mitosis. It is involved in the trafficking and distribution of intermediate filament (IF) proteins and other cellular factors to daughter cells during progenitor cell division. | Additional information: Clone REA575 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesNES, ESTM46
Gene, Accession #Gene ID: 18008, 25491
Catalog #130-119-799
Price$71
Order / More InfoNestin, Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesKachinsky, A. M. et al. (1995) Intermediate filaments in cardiac myogenesis: nestin in the developing mouse heart. J. Histochem. Cytochem. 43 (8): 843-847. | Park, D. et al. (2010) Nestin is required for the proper self-renewal of neural stem cells. Stem Cells 28 (12): 2162-2171. | Yang, J. et al. (2000) Nestin expression during mouse eye and lens development. Mech. Dev. 94 (1-2): 287-291.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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