EGR-2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | EGR-2, Mouse |
| Clone | REA869 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 150 µg in 1 mL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | EGR-2 Antibody, anti-mouse, FITC, REAfinity™. Clone REA869 recognizes the mouse transcription factor EGR-2, also known as early growth response protein 2 or Krox20. EGR-2 consists of three tandem C2H2-type zinc fingers and its expression is induced by EGFR, which is important for osteoprogenitor maintenance and new bone formation. EGR-2 is found primarily in adult thymus, in the embryonic nervous system, and in mammary tumors and plays a critical role in the development of T cells and NKT cells. | Additional information: Clone REA869 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Egr-2, Krox-20, Krox20, Zfp-25 |
| Gene, Accession # | Gene ID: 13654 |
| Catalog # | 130-114-255 |
| Price | $187 |
| Order / More Info | EGR-2, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Warner, L. E. et al. (1998) Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies. Nat. Genet. 18 (4): 382-384. | Dillon, R. L. et al. (2007) An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer. Mol. Cell. Biol. 27 (24): 8648-8657. | Chandra, A. et al. (2013) Epidermal growth factor receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing early growth response 2 (EGR2) expression. J. Biol. Chem. 288 (28): 20488-20498. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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