CD193 (CCR3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD193 (CCR3), Human |
| Clone | REA574 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | VioGreen conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD193 (CCR3) Antibody, anti-human, VioGreen™, REAfinity™. Clone REA574 recognizes the human CD193 antigen, a seven-transmembrane domain G protein-coupled receptor, also known as CCR3. CD193 binds a variety of chemokines, including eotaxin (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26), RANTES (CCL5), MCP-4 (CCL13), leukotactin (CCL15), and MEC (CCL28). CD193 is expressed by eosinophils, basophils, mast cells, platelets, CD34+ hematopoietic progenitor cells, and keratinocytes, as well as by some T cell subsets, in particular T?2 cells. CD193 regulates cell migration and activation and is a co-receptor for HIV. | Additional information: Clone REA574 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | CCR3, CC-CKR-3, CKR3, CMKBR3 |
| Gene, Accession # | Gene ID: 1232 |
| Catalog # | 130-130-450 |
| Price | $385 |
| Order / More Info | CD193 (CCR3), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Ponath, P. D. et al. (1996) Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J. Exp. Med. 183 (6): 2437-2448. | Combadiere, C. et al. (1995) Cloning and functional expression of a human eosinophil CC chemokine receptor. J. Biol. Chem. 270 (28): 16491-16494. | Xiao, L. et al. (1999) Partial resistance to infection by R5X4 primary HIV type 1 isolates in an exposed-uninfected individual homozygous for CCR5 32-base pair deletion. AIDS Res Hum Retroviruses 15 (13): 1201-1208. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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