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Antigenic Specificity | CD19, Mouse |
Clone | REA749 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | APC-Vio 770 conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD19 Antibody, anti-mouse, APC-Vio® 770, REAfinity™. Clone REA749 recognizes the mouse CD19 antigen, a type I transmembrane glycoprotein expressed on B cells throughout their development from the early pro-B cell through the mature B cell stages. Its expression is down-regulated during terminal differentiation to plasma cells. CD19 associates with complement receptor CD21 and with CD81 on the cell surface of mature B cells, thereby forming a multi-molecular complex which signals synergistically to membrane IgM. It is also expressed on follicular dendritic cells and peritoneal mast cells. | Additional information: Clone REA749 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | B4 |
Gene, Accession # | Gene ID: 12478 |
Catalog # | 130-112-038 |
Price | $160 |
Order / More Info | CD19, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Fearon, D. T. (1993) The CD19-CR2-TAPA-1 complex, CD45 and signaling by the antigen receptor of B lymphocytes. Curr. Opin. Immunol. 5 (3): 341-348. | Tedder, T. F. et al. (1994) The CD19/CD21 signal transduction complex of B lymphocytes. Immunol. Today 15 (9): 437-442. | Krop, I. et al. (1996) Self-renewal of B-1 lymphocytes is dependent on CD19. Eur. J. Immunol. 26 (1): 238-242. |