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Antigenic Specificity | CD48, Mouse |
Clone | HM48-1 |
Host Species | Hamster |
Reactive Species | mouse |
Isotype | IgG1 |
Format | purified |
Size | 500 µg in 0.5 mL |
Concentration | n/a |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD48 Antibody, anti-mouse, pure-functional grade. The HM48-1 antibody reacts with the CD48 mouse antigen, which is a 45 kDa GPI-linked glycoprotein also known as BCM1, blast-1 (human), or OX-45 (rat). CD48 belongs to the SLAM family including CD48, CD244, and CD150. These cell surface receptors were differentially expressed among functionally progenitors. Hematopoietic stem cells are highly purified as CD150-CD48-CD244- cells, multipotent hematopoietic progenitors are CD244+CD150-CD48- and most restricted progenitor cells are CD48+CD244+CD150-. In mouse, the ligands for CD48 are CD2 and CD244. |
Immunogen | n/a |
Other Names | BCM1, BLAST, Blast-1, MEM-102, SLAMF2, Sgp-60 |
Gene, Accession # | Gene ID: 12506 |
Catalog # | 130-106-226 |
Price | $385 |
Order / More Info | CD48, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Latchman, Y. et al. (1998) Cutting edge: Identification of the 2B4 molecule as a counter-receptor for CD48. J Immunol 161: 5809-5812. | Kato, K. et al. (1992) CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J. Exp. Med. 176: 1241. | Kiel, M. J. et al. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121 (7): 1109-1121. |