CD223, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityCD223, Mouse
CloneC9B7W
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG1κ
Formatphycoerythrin (PE) conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionCD223 Antibody, anti-mouse, PE. Clone C9B7W recognizes an epitope within the D2 domain of murine CD233, also known as LAG-3, which is a 70 kDa high affinity MHC class II ligand. It is expressed on activated CD4+ and CD8+ α/β T cells and on a subset of NK cells. It has been reported that in association with the CD3 complex CD223 is a negative regulatory molecule to inhibit TCR-mediated signaling and to regulate homeostatic T cell expansion.
Immunogenn/a
Other NamesLAG-3, Ly66
Gene, Accession #Gene ID: 16768
Catalog #130-102-578
Price$71
Order / More InfoCD223, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesWorkman, C. J. et al. (2002) Cutting edge: Molecular analysis of the negative regulatory function of lymphocyte activation gene-3. J Immunol 169 (10): 5392-5395. | Baixeras, E. et al. (1992) Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens. J. Exp. Med. 176 (2): 327-337. | Workman, C. J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur. J. Immunol. 32 (8): 2255-2263.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

macs@miltenyibiotec.de

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