TCRγ/δ, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | TCRγ/δ, Human |
| Clone | REA591 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | PerCP-Vio 700 conjugate |
| Size | 30 tests in 60 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TCRγ/δ Antibody, anti-human, PerCP-Vio® 700, REAfinity™. Clone REA591 recognizes the human TCRγ/δ antigen. The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of an α and a β chain (TCRα/β) or a γ and a δ chain (TCRγ/δ). The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules. | Additional information: Clone REA591 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | TCRgd |
| Gene, Accession # | Gene ID: 6965 |
| Catalog # | 130-114-040 |
| Price | $158 |
| Order / More Info | TCRγ/δ, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Airoldi, I. et al. (2015) γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ+/CD19+ lymphocytes. Blood 125 (15): 2349-2358. | Bonneville, M. et al. (2010) Gammadelta T cell effector functions: a blend of innate programming and acquired plasticity. Nat. Rev. Immunol. 10 (7): 467-478. | Wiest, D. L. (2016) Development of γδ T cells, the special-force soldiers of the immune system. Methods Mol. Biol. 1323: 23-32. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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