CD40, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD40, Mouse |
| Clone | FGK45.5 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | Vio Bright FITC conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD40 Antibody, anti-mouse, Vio® Bright FITC. Clone FGK45.5 recognizes the mouse CD40 antigen, a 40-50 kDa glycoprotein and member of the tumor necrosis factor receptor (TNFR) family. CD40 is expressed on B lymphocytes, macrophages, and dendritic cells. It is an important costimulatory molecule for B cells as well as dendritic cells, monocytes, and other antigen-presenting cells (APCs). The interaction of CD40 on B cells with its ligand CD154 is involved in B cell activation and differentiation; engagement of CD40 on dendritic cells leads to maturation. | Clone FGK45 can be used for blocking of CD40/CD154 interaction and for in vitro and in vivo activation of CD40 expressing APCs. |
| Immunogen | n/a |
| Other Names | Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50 |
| Gene, Accession # | Gene ID: 21939 |
| Catalog # | 130-105-170 |
| Price | $90 |
| Order / More Info | CD40, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Rolink, A. et al. (1996) The SCID but not the RAG-2 gene product is required forS mu-S epsilon heavy chain class switching. Immunity 5 (4): 319-330. | Bonifaz, L. et al. (2002) Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J. Exp. Med. 196: 1627-1638. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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