CD138, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD138, Mouse |
| Clone | REA104 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | PE-Vio 615 conjugate |
| Size | 30 µg in 1 mL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD138 Antibody, anti-mouse, PE-Vio® 615, REAfinity™. CD138, also known as syndecan-1, is a type I integral membrane protein belonging to the syndecan protein family which carries three to five heparan sulfate and chondroitin sulfate chains. CD138 is highly expressed on plasma cells and pre-B cells but not on mature peripheral B cells. It is also expressed on fibroblasts and epithelial cells. The expression of CD138 can be regulated by several cytokines and factors, e.g., thrombin, which is reported to increase the synthesis of CD138 molecules that exhibit high-affinity antithrombin-3 binding. | Additional information: Clone REA104 displays negligible binding to Fc receptors. | |
| Immunogen | n/a |
| Other Names | SDC1, Sstn, Synd, Synd1, SYN-1 |
| Gene, Accession # | Gene ID: 20969 |
| Catalog # | 130-108-989 |
| Price | $167 |
| Order / More Info | CD138, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Cizmeci-Smith, G. et al. (1997) Thrombin stimulates Syndecan-1 promotor activity and expression of a form of Syndecan-1 that binds antithrombin III in vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 17: 2609 -2616. | Sanderson, R. D. et al. (1989) B lymphocytes express and lose syndecan at specific stages of differentiation. Cell Regul. 1 (1): 27-35. | Jalkanen, M. et al. (1985) Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody. J. Cell Biol. 101 (3): 976-984. | Saunders, S. et al. (1989) Molecular cloning of syndecan, an integral membrane proteoglycan. J. Cell Biol. 108 (4): 1547-1556. | Chilosi, M. et al. (1999) CD138/syndecan-1: a useful immunohistochemical marker of normal and neoplastic plasma cells on routine trephine bone marrow biopsies. Mod. Pathol. 12 (12): 1101-1106. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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