CD132, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD132, Mouse |
| Clone | REA403 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | Vio Bright FITC conjugate |
| Size | 9 µg in 300 µL |
| Concentration | 1:10 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD132 Antibody, anti-mouse, Vio® Bright FITC, REAfinity™. Clone REA403 recognizes the mouse CD132 antigen, a 65-70 kDa single-pass type I membrane protein also known as common γ chain, which is shared by the IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21 receptors. CD132 is expressed on T and B lymphocytes, NK cells, monocytes, and granulocytes. It is involved in intracellular signal transduction by associating with effector molecules within the cytoplasm. The most common form of severe combined immune deficiency in humans, with lack of circulating T cells, a normal or increased number of B lymphocytes, and an X-linked pattern of inheritance (XSCID) has been shown to be due to defects of the CD132 gene. | Additional information: Clone REA403 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | IL2RG, IL-2RG, IL2RG, p64, IL-2Rγ |
| Gene, Accession # | Gene ID: 16186 |
| Catalog # | 130-106-182 |
| Price | $90 |
| Order / More Info | CD132, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Andersson, A. et al. (1997) Mouse macrophage development in the absence of the common gamma chain: defining receptor complexes responsible for IL-4 and IL-13 signaling. Eur. J. Immunol. 27 (7): 1762-1768. | DiSanto, J. P. et al. (1994) The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus. Eur. J. Immunol. 24 (12): 3014-3018. | Kumaki, S. et al. (1993) Cloning of the mouse interleukin 2 receptor gamma chain: demonstration of functional differences between the mouse and human receptors. Biochem. Biophys. Res. Commun. 193 (1): 356-363. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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