ESR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | ESR1, Human |
| Clone | REAL887 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ESR1 Antibody, anti-human, PE, REAdye_lease™. Clone REAL887 is an antibody fragment derived from the full ESR1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL887 recognizes the human nuclear receptor ESR1, also known as Estrogen Receptor α or NR3A1, which is widely expressed in several tissues, including liver, lung, kidney, spleen, uterus, ovary, mammary gland, male reproductive organs, bone, heart, hypothalamus, and adipose tissue. ESR1 is a transcription factor composed of several domains, which are essential for hormone and DNA binding, and activation of transcription. Estrogen receptors play a role in pathological processes including breast cancer, endometrial cancer, and osteoporosis. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). | |
| Immunogen | n/a |
| Other Names | Estrogen Receptor α, ESR, NR3A1, Estrogen receptor, ER, ER-alpha, Estradiol receptor |
| Gene, Accession # | n/a |
| Catalog # | 130-126-071 |
| Price | $480 |
| Order / More Info | ESR1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Bondesson, M. et al. (2015) Estrogen receptor signaling during vertebrate development. Biochim. Biophys. Acta 1849 (2): 142-151. | Dahlman-Wright, K. et al. (2006) International Union of Pharmacology. LXIV. Estrogen receptors. Pharmacol. Rev. 58 (4): 773-781. | Paterni, I. et al. (2014) Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential. Steroids 90: 13-29. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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