Edit |   |
---|---|
Antigenic Specificity | TCR Vβ5.1, Human |
Clone | REA1062 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR Vβ5.1 Antibody, anti-human, APC, REAfinity™. Clone REA1062 recognizes the human variable beta 5.1 subunit of the α/β T cell receptor (TCR Vβ5.1), a member of the Ig superfamily. The TCR is a heterodimeric glycoprotein associated with the CD3 antigen. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ5.1 is a variant of the TCR β chain. α/β T cells express a diverse α/β TCR repertoire that specifically co-recognizes self or foreign antigen bound to antigen-presenting molecules, which thereby leads to T cell-mediated immunity. REA1062 does not recognize Vβ5.2 or Vβ5.3. | Additional information: Clone REA1062 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCR Vb5.1, TCR Vbeta5.1, V beta 5.1 |
Gene, Accession # | Gene ID: 28614 |
Catalog # | 130-118-237 |
Price | $325 |
Order / More Info | TCR Vβ5.1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Concannon, P. et al. (1986) Diversity and structure of human T-cell receptor beta-chain variable region genes. Proc. Natl. Acad. Sci. U.S.A. 83 (17): 6598-6602. | Wei, S. et al. (1994) The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics 40 (1): 27-36. |