Mast Cell Tryptase, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Mast Cell Tryptase, Human |
| Clone | REAL798 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | allophycocyanin (APC) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mast Cell Tryptase Antibody, anti-human, APC, REAdye_lease™. Clone REAL798 is an antibody fragment derived from the full Mast Cell Tryptase antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL798 recognizes human mast cell tryptase, an important marker of mast cell activation and inflammatory mediator. Tryptase is involved in angiogenesis after its release from activated MC granules. Tryptase+ mast cell infiltration leads to an unfavorable clinical outcome in solid tumors. Mast Cell Tryptase is appropriate to be a valuable prognostic biomarker for human solid and hematological tumors. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
| Immunogen | n/a |
| Other Names | Tryptase M, mast cell protease II, skin tryptase, lung tryptase, pituitary tryptase, mast cell neutral proteinase, mast cell serine proteinase II, mast cell proteinase II, mast cell serine proteinase tryptase, rat mast cell protease II |
| Gene, Accession # | n/a |
| Catalog # | 130-125-278 |
| Price | $495 |
| Order / More Info | Mast Cell Tryptase, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Vitte, J. (2015) Human mast cell tryptase in biology and medicine. Mol. Immunol. 63 (1): 18-24. | Ribatti, D. et al. (2015) Tryptase, a novel angiogenic factor stored in mast cell granules. Exp. Cell Res. 332 (2): 157-162. | Atiakshin, D. et al. (2018) Tryptase as a polyfunctional component of mast cells. Histochem. Cell Biol. 149 (5): 461-477. | Komi, D. E .A. et al. (2020) Role of Mast Cells in Shaping the Tumor Microenvironment. Clin Rev Allergy Immunol 58 (3): 313-325. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG