PCNA, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG
Search, find, compare suppliers for anti-PCNA, Human/Mouse/Rat antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PCNA, Human/Mouse/Rat |
| Clone | REA858 |
| Host Species | Recombinant Human |
| Reactive Species | human, mouse, rat, nonhuman primate, other |
| Isotype | IgG1 |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests in 200 µL |
| Concentration | 1:50 |
| Applications | Intracellular flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PCNA Antibody, anti-human/mouse/rat, APC, REAfinity™. Clone REA858 recognizes the human, mouse, and rat proliferating cell nuclear antigen (PCNA), a 36 kDa nuclear protein also known as cyclin or auxiliary protein of DNA polymerase delta. PCNA is expressed in the nucleus of all proliferating cells. PCNA plays a role in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Furthermore, it is involved in DNA damage response by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. | Additional information: Clone REA858 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | proliferating-cell-nuclear-antigen, Cyclin |
| Gene, Accession # | Gene ID: 5111, 18538, 25737 |
| Catalog # | 130-114-513 |
| Price | $325 |
| Order / More Info | PCNA, Human/Mouse/Rat Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Landberg, G. et al. (1990) Flow cytometric multiparameter analysis of proliferating cell nuclear antigen/cyclin and Ki-67 antigen: a new view of the cell cycle. Exp. Cell Res. 187 (1): 111-118. | Guzinska-Ustymowicz, K. et al. (2009) Correlation between proliferation markers: PCNA, Ki-67, MCM-2 and antiapoptotic protein Bcl-2 in colorectal cancer. Anticancer Res. 29 (8): 3049-3052. | Cazzalini, O. et al. (2014) CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Nucleic Acids Res. 42 (13): 8433-8448. | Ortega, J. et al. (2015) Phosphorylation of PCNA by EGFR inhibits mismatch repair and promotes misincorporation during DNA synthesis. Proc. Natl. Acad. Sci. U.S.A. 112 (18): 5667-5672. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG