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Antigenic Specificity | γ-Actin 1, Human |
Clone | REAL591 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | n/a |
Format | phycoerythrin (PE) conjugate |
Size | 200 µL |
Concentration | n/a |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | γ-Actin 1 Antibody, anti-human, PE, REAdye_lease™. Clone REAL591 is an antibody fragment derived from the full Anti-γ-Actin 1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL591 recognizes the human gamma actin 1 protein, also known as gamma-cytoplasmic actin, encoded by the ACTG1 gene, and belongs to the actin family which consists of highly conserved proteins. Actin gamma 1 is involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.Genomic mutations of ACTG1 lead to DFNA26, Non-syndromic neurosensory deafness autosomal dominant type 20 or Baraitser-Winter syndrome 2 (BRWS2). | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
Immunogen | n/a |
Other Names | gamma-cytoplasmic actin, γ-actin 1, actin gamma 1, ACTG1 |
Gene, Accession # | n/a |
Catalog # | 130-126-215 |
Price | $475 |
Order / More Info | γ-Actin 1, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Ostler, N. et al. (2014) Gamma interferon-induced guanylate binding protein 1 is a novel actin cytoskeleton remodeling factor. Mol. Cell. Biol. 34 (2): 196-209. | Dong, X. et al. (2018) Actin Gamma 1, a new skin cancer pathogenic gene, identified by the biological feature-based classification. J. Cell. Biochem. 119 (2): 1406-1419. |